Peeriodicals

Select the best science
About
Login Request invitation
Updated May 16, 2024 7 subscribers

COVID, AMYLOID, AND INFLAMMATION

Literature collection of the CovAmInf workgroup.

Editors Joshua T. Berryman Abdul Mannan Baig Artemi Bendandi Daniel Bonhenry Mattheos A.G. Koffas

Invite Editors
List Editors
List Editor Invitations

A case series of cutaneous phosphorylated α-synuclein in Long-COVID POTS (2022)

Mitchell G. Miglis, Jordan Seliger, Ruba Shaik, Christopher H. Gibbons

PubMed: 35570247  DOI: 10.1007/s10286-022-00867-0 

The authors demonstrate the presence of phosphorylated alpha-synuclein (p-aSyn) in the skin of 5 out of 8 patients with long covid postural orthostatic tachycardia syndrome (POTS). P-aSyn is a biomarker for synucleinopathies and was detected using an immunohistochemical method. 3 of the patients showed reduced intraepidermal nerve fiber density. 4 of them exhibited hyposmia. It is estimated that 67% of individuals with long covid have POTS (https://doi.org/10.3389/fneur.2022.1012668). The findings reported in this case series need to be followed-up to better understand the pathophysiology of long covid and assess the risk of neurodegenerative disease.

reply
  • In your name
  • Anonymously
Reply

Subjects

  • Content

  • About us
  • Contact us
  • Follow Us

  • Twitter
  • Legal

  • Terms of service
  • Privacy Policy

Copyright © 2025 The PubPeer Foundation

About Peeriodicals
Have a Question?