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Updated May 16, 2024 7 subscribers

COVID, AMYLOID, AND INFLAMMATION

Literature collection of the CovAmInf workgroup.

Editors Joshua T. Berryman Abdul Mannan Baig Artemi Bendandi Daniel Bonhenry Mattheos A.G. Koffas

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A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets (2023)

Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng, Haiyuan Yu

3 comments on PubPeer PubMed: 36217030  DOI: 10.1038/s41587-022-01474-0 

This COVID interactome shows the (hypothetically) amyloidogenic peptides ORF6 and ORF10 as sharing a large number of host interaction partners. What do all these targets do? Just now I have no idea, but the commonality of ORF6 and ORF10 is very interesting.

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