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Updated May 16, 2024 7 subscribers

COVID, AMYLOID, AND INFLAMMATION

Literature collection of the CovAmInf workgroup.

Editors Joshua T. Berryman Abdul Mannan Baig Artemi Bendandi Daniel Bonhenry Mattheos A.G. Koffas

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Long-term cardiovascular outcomes of COVID-19 (2022)

Yan Xie, Evan Xu, Benjamin Bowe, Ziyad Al-Aly

2 comments on PubPeer DOI: 10.1038/s41591-022-01689-3  PubMed: 35132265 

This study looks at medical records of veterans, identifying substantial cardiovascular risk over the 12 months following SARS-CoV2 infection.

This study is data driven and has been leading people to look for mechanisms and pathways, clotting (perhaps driven by inflammatory processes) in particular has gained a following under the hashtag #teamclots with a number of scientific and journalistic investigations leaning heavily on the data presented here. Existing connections are established in a general way between vascular/haematological problems and neurological disease, via strokes, and also potentially via vascular/cerebrovascular amyloidoses. It is still not clear to this editor (Feb 2023) what relative significance clotting, ischaemia etc might have relative to the other pathways to amyloid disease.

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