11 patients were evaluated for REM sleep behavior disorder (RBD) 60 days after being diagnosed with COVID-19 infection. Video polysomnograms showed evidence of REM sleep without atonia, an early sign of RBD, in 4 of these patients. A separate case-control study, REM sleep without atonia was evident in 9/25 patients following infection compared to 3/25 healthy controls (https://doi.org/10.1093/sleep/zsac079.552). Using an online survey, 21,870 people were asked to self-report symptoms of REM sleep behavior disorder. The prevalence of lifetime and weekly dream-enactment behaviors increased by 1.8- and 2.9-times following COVID-19 infection (https://doi.org/10.1111/jsr.13613). The potential implication of these findings warrants follow-up with a clinical trial using video polysomnogram to determine the risk of RBD subsequent to COVID-19 infection.